أُوْلَٰٓئِكَ ٱلَّذِينَ لَهُمۡ سُوٓءُ ٱلۡعَذَابِ وَهُمۡ فِي ٱلۡأٓخِرَةِ هُمُ ٱلۡأَخۡسَرُونَ ٥
Those are the ones for whom there will be the worst of punishment, and in the Hereafter they are the greatest losers.
Translation: Saheeh International (English)
Each word's meaning and sound
Such people will suffer in the worldly life through trials and humiliation and in the Hereafter they suffer the greatest loss, losing themselves and their families on the Day of Judgement and entering Hell forever.
Al-Mukhtasar in interpreting the Noble Quran